Answer: With fat transfer procedures, regardless of the recipient site or area being treated, the end results are permanent. There is always some amount of volume loss initially following a fat transfer procedure, with graft take varying widely between 20-80%. The fat that does take becomes viable new tissue. Those living cells and tissue will however continue to undergo changes with further aging. Facial fat transfer may be performed as an independent procedure or as an adjunctive procedure with a facelift. Facial rejuvenation with fat transfer alone is most likely to be performed in patients in their 40s. If there is good graft take the effects should be lasting. This is the benefit of fat transfer over temporary fillers. With further aging changes, an additional procedure, either another fat transfer or some type of facelift may be indicated after several years. An additional fat transfer should not be needed after only a few years unless there was inadequate take with the first.